Why You’ll Love This Recipe

Creamy Cajun Chicken Penne Pasta is a bold, flavorful dish that brings together tender chicken breast, smoky Cajun spices, and a rich, creamy sauce tossed with perfectly cooked penne. It’s a restaurant-style comfort food that’s quick enough for weeknights yet impressive enough for entertaining.

ingredients

(Tip: You’ll find the full list of ingredients and measurements in the recipe card below.)

penne pasteboneless, skinless chicken breastsheavy creamparmesan cheesegarlicolive oilCajun seasoningsaltblack pepperpaprikared pepper flakes (optional for extra heat)onionbell peppers (red and green)

directions

Cook the penne pasta according to package instructions, then drain and set aside.

Slice the chicken breasts into thin strips and season them with Cajun seasoning, salt, pepper, and paprika.

Heat olive oil in a large skillet over medium-high heat. Add the seasoned chicken and cook until golden and fully cooked. Remove from skillet and set aside.

In the same skillet, sauté chopped onions and bell peppers until tender.

Add minced garlic and cook for another minute until fragrant.

Pour in the heavy cream and bring to a simmer. Stir in grated Parmesan cheese until the sauce thickens.

Return the cooked chicken to the skillet and combine with the creamy sauce.

Add the drained pasta to the sauce and toss everything together until well coated.

Sprinkle red pepper flakes for extra spice if desired and serve hot.

Servings and timing

This recipe yields approximately 4 servings.Preparation time: 10 minutesCooking time: 20 minutesTotal time: 30 minutes

Variations

Use shrimp instead of chicken for a seafood twist.

Add spinach or mushrooms for extra veggies.

Swap penne for fettuccine or rigatoni if preferred.

Make it dairy-free by using coconut milk and vegan cheese alternatives.

storage/reheating

Store leftovers in an airtight container in the refrigerator for up to 3 days.Reheat on the stovetop over low heat, adding a splash of cream or milk to loosen the sauce.Microwave reheating also works—cover and heat in 30-second intervals, stirring in between.

FAQs

What is Cajun seasoning made of?

Typically a mix of paprika, garlic powder, onion powder, cayenne, oregano, thyme, and black pepper.

Can I make this dish less spicy?

Yes, reduce or omit the red pepper flakes and use a milder Cajun blend.

Can I use pre-cooked chicken?

Yes, just add it at the end to heat through.

Is this recipe gluten-free?

Not by default, but you can substitute with gluten-free pasta and ensure all seasonings are gluten-free.

Can I freeze this pasta?

It’s best enjoyed fresh, but it can be frozen. Reheat gently to preserve the sauce texture.

Can I use milk instead of cream?

You can, but the sauce will be thinner. For a richer taste, stick with heavy cream.

What vegetables pair well with this dish?

Bell peppers, onions, mushrooms, and spinach are great additions.

Conclusion

Creamy Cajun Chicken Penne Pasta delivers the perfect balance of spice and creaminess in every bite. Whether you’re craving a cozy meal or cooking for guests, this dish is an easy, satisfying way to bring bold Southern-inspired flavors to your table.