Why You’ll Love This Recipe

Southwest Chicken Alfredo is a bold fusion of creamy Italian Alfredo sauce and zesty Southwest flavors. This hearty pasta dish features tender chicken, smoky spices, and colorful veggies tossed in a rich, cheesy sauce. Perfect for a comforting weeknight dinner or entertaining guests, it delivers both flavor and flair in every bite.

ingredients

(Tip: You’ll find the full list of ingredients and measurements in the recipe card below.)

chicken breast (boneless, skinless)olive oilgarlic powderchili powdersmoked paprikacuminonionsbell peppers (red, yellow, or green)jalapeñogarlicheavy creamparmesan cheesefettuccine or penne pastasalt and pepperfresh cilantro (optional for garnish)lime wedges (optional)

directions

Cook the pasta according to package instructions, then drain and set aside.

Season chicken breasts with garlic powder, chili powder, smoked paprika, cumin, salt, and pepper.

Heat olive oil in a large skillet over medium heat. Cook the chicken until golden and fully cooked, then remove and slice.

In the same skillet, sauté chopped onions, bell peppers, jalapeño, and garlic until soft and fragrant.

Reduce heat and pour in the heavy cream, stirring to combine with the veggies.

Add grated Parmesan cheese and stir until melted into a smooth sauce.

Return the sliced chicken to the skillet, stirring to coat with the sauce.

Add the cooked pasta and toss until everything is well coated and heated through.

Garnish with fresh cilantro and a squeeze of lime if desired.

Servings and timing

This recipe serves 4 people.Preparation time: 15 minutesCooking time: 25 minutesTotal time: 40 minutes

Variations

Substitute shrimp or grilled steak for the chicken.

Use rotini or bowtie pasta instead of fettuccine.

Add black beans or corn for extra texture and Southwest flair.

Top with shredded pepper jack or Monterey Jack cheese for added spice.

Mix in spinach or kale for a touch of green and nutrition.

storage/reheating

Store leftovers in an airtight container in the refrigerator for up to 4 days.Reheat on the stovetop over low heat with a splash of cream or milk to loosen the sauce.You can also microwave in 30-second intervals, stirring between each until heated through.

FAQs

Is this dish spicy?

It has a mild to moderate heat, but you can adjust by using less or more jalapeño and chili powder.

Can I use store-bought Alfredo sauce?

Yes, but homemade provides a fresher and richer flavor.

What type of chicken works best?

Boneless, skinless chicken breast or thighs both work well.

Can I make this dish ahead of time?

Yes, but add the pasta just before serving to prevent it from soaking up too much sauce.

Is this dish gluten-free?

Use gluten-free pasta and confirm all seasonings and cheese are gluten-free.

Can I freeze Southwest Chicken Alfredo?

It’s best enjoyed fresh, but you can freeze it for up to 2 months. Reheat slowly and stir often.

What vegetables go well in this dish?

Onions, peppers, jalapeños, corn, and even mushrooms complement the flavors well.

How do I keep the sauce from separating?

Keep the heat low while adding the cheese and stir continuously until melted.

Can I use milk instead of cream?

Yes, but the sauce will be thinner and less rich.

Can I make it vegetarian?

Absolutely—omit the chicken and add more veggies or use a plant-based protein.

Conclusion

Southwest Chicken Alfredo brings the best of both worlds—creamy comfort and bold spice—into one irresistible meal. Whether you’re cooking for family or impressing guests, this dish delivers delicious results with minimal effort. It’s a fun and flavorful twist on classic Alfredo that’s sure to become a favorite in your kitchen.